The movie had the biggest opening day ever for an R-rated film as well.

20th Century Fox's new comic book film set a record high for both President's Day weekend and the month of February, eclipsing Fifty Shades of Grey's previous leading debut of $85.2 million.

On top of that, Deadpool's opening weekend now stands as the biggest ever for an R-rated film, outpacing The Matrix Reloaded's $91.8 million debut.

Deadpool earned an additional $125 million overseas, bringing its total global opening to a massive $260 million.